There is not option to change the opacity. However, you can change the size and location by editing [ Interface > AddOns > nUI > Layouts > Default > UnitPanels > {panel mode} > nUI_UnitSkin_{panel mode}_{unit id}.lua ]
Just locate the auras section and you'll see the option there for size on both the help and harm auras.
There's also a plugin you can find in the "nUI: Unit Frame Panels" section called nUI Aura Buttons which entirely changes the style and location of the auras.
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