To be perfectly honest, I don't do macros much... so I'm not of much use to you there. That said, nUI does not "handle" macros at all. you just create your macro and put it on the action bar. From there on out, it's all done by the Blizzard code. I'm not sure why Fear would work and banish would not, other than that you can fear almost any target (focus) but you can only banish a demon.
Maybe one of the macro gurus who read over our shoulders can lend a hand?
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