You can move it, but it is not a trivial task because other frames are anchored to it and will move when you move it.
To move the focus, you'll need to edit [ Interface > AddOns > nUI > Layouts > Default > UnitPanels > {panel mode} > nUI_UnitPanel_{panel mode}.lua ] and locate the section for the focus frame, then change the "xOfs" and "yOfs" anchor values to move it.
Save your changes after you make them and then do a '/nui rl' to reload the UI and see your changes. You may then need to move other frames that moved with it.
That said, it's pretty rare that you need the focus frame and the minimap at the same time isn't it? But, if you are in a situation where you need both, you could always use the '/nui minimap' option to return the minimap to the upper right corner of the display.
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