You have the zygor guide addon ?
Does it work without the infopanel plugin for it active ?
Have you checked to see if the version of zygor you have is different from the one that the infopanel is designed for ?
Zygor :
http://www.zygorguides.com/
Zygor InfoPanel :
http://www.wowinterface.com/download...anelZygor.html
If you haven't got Zygor installed the InfoPanel won't work. If you don't have the InfoPanel but you have Zygor then it will show somewhere else on the screen.