We know stripping the mini map is possible, I assume the info mini map mover plugin does this. This leaves the location.lua calls on the frame anchor for dashboard?
So we'd need another blank.lua skin? that doesn't call these functions? add a button state in main? Not sure here, just thinking out load is all.
I wish I was a programmer I really do. Anyway, if its not doable, I shall strip the code and hope it doesn't break on me to completely remove all unit frames from the package. Then just create a copy of my wow folder for loading my alts that use the out of the box nUI.