I play with an N52 also, with the same 6, 11 as Shift and Ctrl also, and I like the idea of what you have done. One question though, is there a way to make it so the cast bar is 5 on top, 4 in the middle, and 3 underneath like the N52 is when it is set up that way.
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That way it is more visual / tactile what we are hitting?
And just out of curiosity what do you have the other buttons and wheel set up as. I use the Thumb button for Vent, and Up D-pad For Mumble, and the wheel up for tab, and down for next PvP target, click last target.