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The tooltip scale is controlled by the "Use UI Scale" option in the video interface options for WoW. As for moving the cast bar, you would have to edit [ Interface > AddOns > nUI > Layouts > Default > HUDLayouts > {HUD mode} > nUI_HUDSkin_{HUD mode}_Player.lua ] and locate the ["Casting"] section. You move the bar by modifying the xOfs (horizontal offset) and yOfs (vertical offset) elements of the anchor section.
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