Verttex is right there. I'm not 100% sure but I thought it worked before Blizz introduced some more secure frames which meant a rewrite of the buff addons.
The nUI aura plugin however has the ability to show tooltips and the debuffs in the center of the screen can be set up to be 'interactive'.
Unfortunately we are stuck with these options as version 5.0 is pretty much at its peak and will be replaced with version 6 once Scott has finished it.
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