Originally Posted by Phanx
Yes; install an addon that replaces it with something else. oUF Phanx does not include a rune bar (yet) so it would not make sense to hide it. Any addon that actually provides a custom rune bar should hide the default one.
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Before i had perl but it was too much and oUF is nice with oUF_Phanx.
I Have for Runes only
http://www.curse.com/addons/wow/magicrunes 