In the TipTop config window, scroll down until you see the anchor settings. You may either anchor the mouse to the cursor, or to a side/corner of the screen. Note that x,y offsets only work when the tip is *not* anchored to the cursor. This is a limitation set by the game's API, and I will not code in the hacks that other tooltip addons use to get around this. I suggest using the alpha setting instead so the tip doesn't block your view so much.